Mehmet Toner Selected Research

Lab-On-A-Chip Devices

5/2016	Clusters of circulating tumor cells traverse capillary-sized vessels.
7/2015	A microfluidic device for label-free, physical capture of circulating tumor cell clusters.
11/2014	Brain tumor cells in circulation are enriched for mesenchymal gene expression.
7/2012	RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis.
7/2010	Burn injury reduces neutrophil directional migration speed in microfluidic devices.
9/2009	Spontaneous migration of cancer cells under conditions of mechanical confinement.
7/2008	Detection of mutations in EGFR in circulating lung-cancer cells.

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Mehmet Toner Research Topics

Disease

47	Neoplasms (Cancer) 01/2022 - 03/2006
22	Circulating Neoplastic Cells 01/2022 - 07/2008
18	Neoplasm Metastasis (Metastasis) 01/2022 - 03/2006
14	Breast Neoplasms (Breast Cancer) 01/2022 - 10/2012
9	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 03/2010
9	Dehydration (Water Stress) 10/2019 - 08/2004
6	Burns 07/2010 - 06/2002
5	Wounds and Injuries (Trauma) 11/2010 - 11/2002
5	Acute Liver Failure (Fulminant Hepatic Failure) 05/2007 - 01/2002
4	Melanoma (Melanoma, Malignant) 01/2021 - 05/2014
4	Hepatocellular Carcinoma (Hepatoma) 01/2017 - 04/2009
4	Liver Failure 02/2008 - 01/2002
3	Hypoxia (Hypoxemia) 12/2020 - 05/2011
3	Inflammation (Inflammations) 12/2020 - 02/2003
3	Infections 12/2020 - 07/2006
3	Lung Neoplasms (Lung Cancer) 01/2017 - 03/2016
2	Brain Neoplasms (Brain Tumor) 12/2020 - 11/2014
2	Sepsis (Septicemia) 12/2020 - 01/2019
2	Carcinogenesis 01/2019 - 01/2016
2	Acquired Immunodeficiency Syndrome (AIDS) 03/2015 - 11/2009
2	Pancreatic Neoplasms (Pancreatic Cancer) 09/2014 - 07/2012
2	Disease Progression 02/2013 - 02/2011
2	Bacterial Infections (Bacterial Infection) 05/2009 - 08/2006
2	Body Weight (Weight, Body) 09/2006 - 06/2002
1	Ischemia 10/2019
1	Neoplasm Micrometastasis 01/2019
1	Glioblastoma (Glioblastoma Multiforme) 12/2018
1	Thrombosis (Thrombus) 01/2018
1	Fibrosis (Cirrhosis) 01/2017
1	Communicable Diseases (Infectious Diseases) 01/2017
1	Hepatitis 01/2017

Drug/Important Bio-Agent (IBA)

23	RNA (Ribonucleic Acid)IBA 01/2022 - 02/2010
10	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2002
9	Biomarkers (Surrogate Marker)IBA 01/2020 - 12/2007
8	Pharmaceutical PreparationsIBA 01/2022 - 11/2009
7	Biological ProductsIBA 01/2019 - 02/2010
4	LigandsIBA 07/2021 - 01/2017
4	EpitopesIBA 01/2020 - 04/2013
4	Androgen Receptors (Androgen Receptor)IBA 01/2018 - 11/2012
3	Epithelial Cell Adhesion MoleculeIBA 01/2022 - 04/2012
3	DNA (Deoxyribonucleic Acid)IBA 07/2021 - 07/2008
3	Estrogen ReceptorsIBA 07/2021 - 07/2014
3	AndrogensIBA 01/2018 - 11/2012
3	TrehaloseIBA 06/2010 - 02/2006
3	Insulin (Novolin)FDA Link 09/2006 - 06/2002
2	Phosphotransferases (Kinase)IBA 01/2022 - 05/2015
2	AntioxidantsIBA 01/2021 - 01/2018
2	NitrogenIBA 10/2019 - 06/2002
2	Indicators and Reagents (Reagents)IBA 01/2018 - 07/2010
2	Tyrosine Kinase InhibitorsIBA 03/2016 - 07/2008
2	GelatinIBA 03/2015 - 09/2006
2	CollagenIBA 12/2014 - 02/2003
2	IceIBA 06/2009 - 06/2008
2	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2007 - 05/2006
1	tyrosine receptor (receptor, tyrosine)IBA 01/2022
1	ChromatinIBA 10/2021
1	Aromatase InhibitorsIBA 07/2021
1	Hormones (Hormone)IBA 07/2021
1	IronIBA 01/2021
1	ferrostatin-1IBA 01/2021
1	Vitamin E FDA LinkGeneric 01/2021
1	Transferrin (beta 2 Transferrin)IBA 01/2021
1	Small Interfering RNA (siRNA)IBA 12/2020
1	Histones (Histone)IBA 12/2020
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2020
1	Cell-Free Nucleic AcidsIBA 01/2020
1	Ribosomal Proteins (Ribosomal Protein)IBA 01/2020
1	olaparibIBA 01/2020
1	AntigensIBA 01/2020
1	Chimeric Antigen ReceptorsIBA 12/2019
1	Celecoxib (Celebrex)FDA Link 01/2019
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2019
1	neratinibIBA 01/2019
1	ProlactinIBA 01/2019
1	Dinoprostone (PGE2)FDA Link 01/2019
1	Prolactin Receptors (Prolactin Receptor)IBA 01/2019
1	Messenger RNA (mRNA)IBA 12/2018
1	epidermal growth factor receptor VIIIIBA 12/2018
1	Tirofiban (Aggrastat)FDA Link 01/2018
1	abirateroneIBA 01/2018
1	Immune Checkpoint InhibitorsIBA 01/2018
1	Acetylcysteine (Siran)FDA LinkGeneric 01/2018
1	Glutathione (Reduced Glutathione)IBA 01/2018
1	Glycoproteins (Glycoprotein)IBA 01/2018
1	Sulfhydryl Compounds (Thiols)IBA 01/2018
1	von Willebrand FactorIBA 01/2018
1	GlobinsIBA 01/2017
1	Circulating Tumor DNAIBA 03/2016
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2016

Therapy/Procedure

20	Therapeutics 01/2022 - 01/2002
7	Lab-On-A-Chip Devices 05/2016 - 07/2008
7	Artificial Liver (Bioartificial Liver) 02/2008 - 01/2002
4	Liver Transplantation 01/2007 - 01/2002
2	Castration 01/2018 - 11/2012
2	Transplantation 12/2014 - 07/2006
1	Injections 12/2020
1	Immunotherapy 12/2019
1	Organ Transplantation 10/2019
1	Treatment Delay 01/2019
1	Neoadjuvant Therapy 10/2018